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SPARC silencing inhibits the growth of acute myeloid leukemia transformed from myelodysplastic syndrome via induction of cell cycle arrest and apoptosis

Secreted protein acidic and rich in cysteine (SPARC) plays key roles in erythropoiesis; haploinsufficiency of SPARC is implicated in the progression of the 5q- syndrome. However, the role of SPARC in other subtypes of myelodysplastic syndrome (MDS) is not fully understood, particularly in the del(5q...

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Detalles Bibliográficos
Autores principales: NIAN, QING, XIAO, QING, WANG, LI, LUO, JING, CHEN, LI-PING, YANG, ZE-SONG, LIU, LIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976133/
https://www.ncbi.nlm.nih.gov/pubmed/24535175
http://dx.doi.org/10.3892/ijmm.2014.1648