Profile of vintafolide (EC145) and its use in the treatment of platinum-resistant ovarian cancer

OBJECTIVE: Our aim was to review the profile of vintafolide (EC145) and its rationale for use in platinum-resistant ovarian cancer. First we investigated the folate receptors (FRs), folate’s pathway into cells, and its expression in normal and cancerous cells, before detailing the mechanism of actio...

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Detalles Bibliográficos
Autores principales: Luyckx, Mathieu, Votino, Raffaella, Squifflet, Jean-Luc, Baurain, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976235/
https://www.ncbi.nlm.nih.gov/pubmed/24729732
http://dx.doi.org/10.2147/IJWH.S39696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976235/
https://www.ncbi.nlm.nih.gov/pubmed/24729732
http://dx.doi.org/10.2147/IJWH.S39696

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