Cargando…
Ca(V)3.2 T-Type Calcium Channels in Peripheral Sensory Neurons Are Important for Mibefradil-Induced Reversal of Hyperalgesia and Allodynia in Rats with Painful Diabetic Neuropathy
We recently showed that streptozotocin (STZ) injections in rats lead to the development of painful peripheral diabetic neuropathy (PDN) accompanied by enhancement of Ca(V)3.2 T-type calcium currents (T-currents) and hyperexcitability in dorsal root ganglion (DRG) neurons. Here we used the classical...
Autores principales: | Obradovic, Aleksandar Lj., Hwang, Sung Mi, Scarpa, Joseph, Hong, Sung Jun, Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976247/ https://www.ncbi.nlm.nih.gov/pubmed/24705276 http://dx.doi.org/10.1371/journal.pone.0091467 |
Ejemplares similares
-
Glycosylation of Ca(V)3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes
por: Joksimovic, Sonja Lj., et al.
Publicado: (2020) -
The Mechanisms of Plasticity of Nociceptive Ion Channels in Painful Diabetic Neuropathy
por: Joksimovic, Sonja L., et al.
Publicado: (2022) -
Selective T-Type Calcium Channel Blockade Alleviates Hyperalgesia in ob/ob Mice
por: Latham, Janelle R., et al.
Publicado: (2009) -
Opioid-induced hyperalgesia: Are thalamic T-type calcium channels treatment targets?
por: Todorovic, Slobodan M.
Publicado: (2022) -
Alpha lipoic acid attenuates evoked and spontaneous pain following surgical skin incision in rats
por: Joksimovic, Sonja Lj., et al.
Publicado: (2021)