Enhanced Specificity of TPMT*2 Genotyping Using Unidirectional Wild-Type and Mutant Allele-Specific Scorpion Primers in a Single Tube

Genotyping of thiopurine S-methyltransferase (TPMT) is recommended for predicting the adverse drug response of thiopurines. In the current study, a novel version of allele-specific PCR (AS-PCR), termed competitive real-time fluorescent AS-PCR (CRAS-PCR) was developed to analyze the TPMT*2 genotype i...

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Detalles Bibliográficos
Autores principales: Chen, Dong, Yang, Zhao, Xia, Han, Huang, Jun-Fu, Zhang, Yang, Jiang, Tian-Nun, Wang, Gui-Yu, Chuai, Zheng-Ran, Fu, Wei-Ling, Huang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976262/
https://www.ncbi.nlm.nih.gov/pubmed/24705376
http://dx.doi.org/10.1371/journal.pone.0091824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976262/
https://www.ncbi.nlm.nih.gov/pubmed/24705376
http://dx.doi.org/10.1371/journal.pone.0091824

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