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Echicetin Coated Polystyrene Beads: A Novel Tool to Investigate GPIb-Specific Platelet Activation and Aggregation

von Willebrand factor/ristocetin (vWF/R) induces GPIb-dependent platelet agglutination and activation of αIIbβ3 integrin, which also binds vWF. These conditions make it difficult to investigate GPIb-specific signaling pathways in washed platelets. Here, we investigated the specific mechanisms of GPI...

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Detalles Bibliográficos
Autores principales: Navdaev, Alexey, Subramanian, Hariharan, Petunin, Alexey, Clemetson, Kenneth J., Gambaryan, Stepan, Walter, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976279/
https://www.ncbi.nlm.nih.gov/pubmed/24705415
http://dx.doi.org/10.1371/journal.pone.0093569