Pancreatic Alpha-Cell Dysfunction Contributes to the Disruption of Glucose Homeostasis and Compensatory Insulin Hypersecretion in Glucocorticoid-Treated Rats

Glucocorticoid (GC)-based therapies can cause insulin resistance (IR), glucose intolerance, hyperglycemia and, occasionally, overt diabetes. Understanding the mechanisms behind these metabolic disorders could improve the management of glucose homeostasis in patients undergoing GC treatment. For this...

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Detalles Bibliográficos
Autores principales: Rafacho, Alex, Gonçalves-Neto, Luiz M., Santos-Silva, Junia C., Alonso-Magdalena, Paloma, Merino, Beatriz, Taboga, Sebastião R., Carneiro, Everardo M., Boschero, Antonio C., Nadal, Angel, Quesada, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976288/
https://www.ncbi.nlm.nih.gov/pubmed/24705399
http://dx.doi.org/10.1371/journal.pone.0093531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976288/
https://www.ncbi.nlm.nih.gov/pubmed/24705399
http://dx.doi.org/10.1371/journal.pone.0093531

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