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Reversal of Ischemic Cardiomyopathy with Sca-1(+) Stem Cells Modified with Multiple Growth Factors

BACKGROUND: We hypothesized that bone marrow derived Sca-1(+) stem cells (BM Sca-1(+)) transduced with multiple therapeutic cytokines with diverse effects will induce faster angiomyogenic differentiation in the infarcted myocardium. METHODS AND RESULTS: BM Sca-1(+) were purified from transgenic male...

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Detalles Bibliográficos
Autores principales: Li, Ning, Pasha, Zeeshan, Ashraf, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976296/
https://www.ncbi.nlm.nih.gov/pubmed/24705272
http://dx.doi.org/10.1371/journal.pone.0093645