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Long-Term Weight-Loss in Gastric Bypass Patients Carrying Melanocortin 4 Receptor Variants
BACKGROUND: The melanocortin 4 receptor (MC4R) critically regulates feeding and satiety. Rare variants in MC4R are predominantly found in obese individuals. Though some rare variants in MC4R discovered in patients have defects in localization, ligand binding and signaling to cAMP, many have no recog...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976318/ https://www.ncbi.nlm.nih.gov/pubmed/24705671 http://dx.doi.org/10.1371/journal.pone.0093629 |