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Long-Term Weight-Loss in Gastric Bypass Patients Carrying Melanocortin 4 Receptor Variants

BACKGROUND: The melanocortin 4 receptor (MC4R) critically regulates feeding and satiety. Rare variants in MC4R are predominantly found in obese individuals. Though some rare variants in MC4R discovered in patients have defects in localization, ligand binding and signaling to cAMP, many have no recog...

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Detalles Bibliográficos
Autores principales:	Moore, Bryn S., Mirshahi, Uyenlinh L., Yost, Evan A., Stepanchick, Ann N., Bedrin, Michael D., Styer, Amanda M., Jackson, Kathryn K., Still, Christopher D., Breitwieser, Gerda E., Gerhard, Glenn S., Carey, David J., Mirshahi, Tooraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976318/ https://www.ncbi.nlm.nih.gov/pubmed/24705671 http://dx.doi.org/10.1371/journal.pone.0093629

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