Parathyroid Hormone Administration Improves Bone Marrow Microenvironment and Partially Rescues Haematopoietic Defects in Bmi1-Null Mice

The epigenetic regulator Bmi1 is key in haematopoietic stem cells, and its inactivation leads to defects in haematopoiesis. Parathyroid hormone (PTH), an important modulator of bone homeostasis, also regulates haematopoiesis, so we asked whether PTH administration improves bone marrow microenvironme...

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Detalles Bibliográficos
Autores principales: Lu, Ruinan, Wang, Qian, Han, Yongli, Li, Jianyong, Yang, Xiang-Jiao, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976339/
https://www.ncbi.nlm.nih.gov/pubmed/24705625
http://dx.doi.org/10.1371/journal.pone.0093864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976339/
https://www.ncbi.nlm.nih.gov/pubmed/24705625
http://dx.doi.org/10.1371/journal.pone.0093864

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