Hsp90 Blockers Inhibit Adipocyte Differentiation and Fat Mass Accumulation

Geldanamycin derivatives are benzoquinone ansamycin antibiotics that bind to Hsp90 and alter its function. The alteration of Hsp90 activity limits some cellular hormonal responses by inhibiting nuclear receptors activation. The nuclear receptors activity, such as PPARγ, the mineralocorticoid and glu...

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Detalles Bibliográficos
Autores principales: Desarzens, Sébastien, Liao, Wan-Hui, Mammi, Caterina, Caprio, Massimiliano, Faresse, Nourdine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976389/
https://www.ncbi.nlm.nih.gov/pubmed/24705830
http://dx.doi.org/10.1371/journal.pone.0094127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976389/
https://www.ncbi.nlm.nih.gov/pubmed/24705830
http://dx.doi.org/10.1371/journal.pone.0094127

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