In Silico Analysis Reveals Sequential Interactions and Protein Conformational Changes during the Binding of Chemokine CXCL-8 to Its Receptor CXCR1

Chemokine CXCL-8 plays a central role in human immune response by binding to and activate its cognate receptor CXCR1, a member of the G-protein coupled receptor (GPCR) family. The full-length structure of CXCR1 is modeled by combining the structures of previous NMR experiments with those from homolo...

Descripción completa

Detalles Bibliográficos
Autores principales: Liou, Je-Wen, Chang, Fang-Tzu, Chung, Yi, Chen, Wen-Yi, Fischer, Wolfgang B., Hsu, Hao-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976404/
https://www.ncbi.nlm.nih.gov/pubmed/24705928
http://dx.doi.org/10.1371/journal.pone.0094178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976404/
https://www.ncbi.nlm.nih.gov/pubmed/24705928
http://dx.doi.org/10.1371/journal.pone.0094178

Ejemplares similares