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Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia

The endocannabinoid anandamide (AEA) is an antinociceptive lipid that is inactivated through cellular uptake and subsequent catabolism by fatty acid amide hydrolase (FAAH). Fatty acid binding proteins (FABPs) are intracellular carriers that deliver AEA and related N-acylethanolamines (NAEs) to FAAH...

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Detalles Bibliográficos
Autores principales: Kaczocha, Martin, Rebecchi, Mario J., Ralph, Brian P., Teng, Yu-Han Gary, Berger, William T., Galbavy, William, Elmes, Matthew W., Glaser, Sherrye T., Wang, Liqun, Rizzo, Robert C., Deutsch, Dale G., Ojima, Iwao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976407/
https://www.ncbi.nlm.nih.gov/pubmed/24705380
http://dx.doi.org/10.1371/journal.pone.0094200