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Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia
The endocannabinoid anandamide (AEA) is an antinociceptive lipid that is inactivated through cellular uptake and subsequent catabolism by fatty acid amide hydrolase (FAAH). Fatty acid binding proteins (FABPs) are intracellular carriers that deliver AEA and related N-acylethanolamines (NAEs) to FAAH...
Autores principales: | Kaczocha, Martin, Rebecchi, Mario J., Ralph, Brian P., Teng, Yu-Han Gary, Berger, William T., Galbavy, William, Elmes, Matthew W., Glaser, Sherrye T., Wang, Liqun, Rizzo, Robert C., Deutsch, Dale G., Ojima, Iwao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976407/ https://www.ncbi.nlm.nih.gov/pubmed/24705380 http://dx.doi.org/10.1371/journal.pone.0094200 |
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