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Disruption of mutated BRAF signaling modulates thyroid cancer phenotype

BACKGROUND: Thyroid cancer is the most common endocrine-related cancer in the United States and its incidence is rising rapidly. Since among various genetic lesions identified in thyroid cancer, the BRAFV600E mutation is found in 50% of papillary thyroid cancers and 25% of anaplastic thyroid cancers...

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Detalles Bibliográficos
Autores principales: Hanly, Elyse K, Rajoria, Shilpi, Darzynkiewicz, Zbigniew, Zhao, Hong, Suriano, Robert, Tuli, Neha, George, Andrea L, Bednarczyk, Robert, Shin, Edward J, Geliebter, Jan, Tiwari, Raj K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976539/
https://www.ncbi.nlm.nih.gov/pubmed/24673746
http://dx.doi.org/10.1186/1756-0500-7-187