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Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production
BACKGROUND: It has been reported that GLP-1 agonist exenatide (exendin-4) decreases blood pressure. The dose-dependent vasodilator effect of exendin-4 has previously been demonstrated, although the precise mechanism is not thoroughly described. Here we have aimed to provide in vitro evidence for the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976540/ https://www.ncbi.nlm.nih.gov/pubmed/24693878 http://dx.doi.org/10.1186/1475-2840-13-69 |