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Unravelling mitochondrial pathways to Parkinson's disease

Mitochondria are essential for cellular function due to their role in ATP production, calcium homeostasis and apoptotic signalling. Neurons are heavily reliant on mitochondrial integrity for their complex signalling, plasticity and excitability properties, and to ensure cell survival over decades. T...

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Detalles Bibliográficos
Autores principales: Celardo, I, Martins, L M, Gandhi, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976614/
https://www.ncbi.nlm.nih.gov/pubmed/24117181
http://dx.doi.org/10.1111/bph.12433