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Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration
The eukaryotic cell possesses specialized pathways to turn over and degrade redundant proteins and organelles. Each pathway is unique and responsible for degradation of distinctive cytosolic material. The ubiquitin-proteasome system and autophagy (chaperone-mediated, macro, micro and organelle speci...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976615/ https://www.ncbi.nlm.nih.gov/pubmed/24116849 http://dx.doi.org/10.1111/bph.12453 |