Perinatal Hypoxia-Ischemia Reduces α7 Nicotinic Receptor Expression and Selective α7 Nicotinic Receptor Stimulation Suppresses Inflammation and Promotes Microglial Mox Phenotype

Inflammation plays a central role in neonatal brain injury. During brain inflammation the resident macrophages of the brain, the microglia cells, are rapidly activated. In the periphery, α7 nicotinic acetylcholine receptors (α7R) present on macrophages can regulate inflammation by suppressing cytoki...

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Detalles Bibliográficos
Autores principales: Hua, Sansan, Ek, C. Joakim, Mallard, Carina, Johansson, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976804/
https://www.ncbi.nlm.nih.gov/pubmed/24757672
http://dx.doi.org/10.1155/2014/718769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976804/
https://www.ncbi.nlm.nih.gov/pubmed/24757672
http://dx.doi.org/10.1155/2014/718769

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