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Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine

Molecular targeted therapy has been developed for cancer chemoprevention and treatment. Cancer cells process a fundamental change in its bioenergetic metabolism from normal cells on an altered lipid metabolism, also known as the de novo fatty acid synthesis, for sustaining their high proliferation r...

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Detalles Bibliográficos
Autores principales: Cheng, Chien-shan, Wang, Zhiyu, Chen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976840/
https://www.ncbi.nlm.nih.gov/pubmed/24778702
http://dx.doi.org/10.1155/2014/232946