EZH2 Silencing with RNA Interference Induces G(2)/M Arrest in Human Lung Cancer Cells In Vitro

Nonsmall-cell lung cancer has a high mortality rate and poor prognosis. In the present study, we silenced EZH2 and explored the consequent cell cycle changes. The expression of cell-cycle-related proteins, including p53, p21, Cdc2, and cyclin B1, was detected with western blotting, and the cell cycl...

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Detalles Bibliográficos
Autores principales: Xia, Hui, Zhang, Wen, Li, Yingjie, Guo, Nannan, Yu, Changhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976908/
https://www.ncbi.nlm.nih.gov/pubmed/24745014
http://dx.doi.org/10.1155/2014/348728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976908/
https://www.ncbi.nlm.nih.gov/pubmed/24745014
http://dx.doi.org/10.1155/2014/348728

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