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EZH2 Silencing with RNA Interference Induces G(2)/M Arrest in Human Lung Cancer Cells In Vitro

Nonsmall-cell lung cancer has a high mortality rate and poor prognosis. In the present study, we silenced EZH2 and explored the consequent cell cycle changes. The expression of cell-cycle-related proteins, including p53, p21, Cdc2, and cyclin B1, was detected with western blotting, and the cell cycl...

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Detalles Bibliográficos
Autores principales:	Xia, Hui, Zhang, Wen, Li, Yingjie, Guo, Nannan, Yu, Changhai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976908/ https://www.ncbi.nlm.nih.gov/pubmed/24745014 http://dx.doi.org/10.1155/2014/348728

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