The dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer

We have recently demonstrated that the combination of gemcitabine and a superoxide dismutase mimetic protects mice against lung cancer by suppressing the functions of myeloid-derived suppressor cells and by activating memory CD8(+) T-cell responses. Persistent memory cells exhibited a glycolytic met...

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Detalles Bibliográficos
Autores principales: Sawant, Anandi, Schafer, Cara C, Ponnazhagan, Selvarangan, Deshane, Jessy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976979/
https://www.ncbi.nlm.nih.gov/pubmed/24711958
http://dx.doi.org/10.4161/onci.27401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976979/
https://www.ncbi.nlm.nih.gov/pubmed/24711958
http://dx.doi.org/10.4161/onci.27401

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