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The dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer
We have recently demonstrated that the combination of gemcitabine and a superoxide dismutase mimetic protects mice against lung cancer by suppressing the functions of myeloid-derived suppressor cells and by activating memory CD8(+) T-cell responses. Persistent memory cells exhibited a glycolytic met...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976979/ https://www.ncbi.nlm.nih.gov/pubmed/24711958 http://dx.doi.org/10.4161/onci.27401 |