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Polyamine blockade promotes antitumor immunity

The levels of polyamines are elevated in neoplastic lesions as compared with normal tissues, and cancer cells tend to manifest a robust dependence on these compounds for proliferation and survival. We have recently demonstrated that a novel approach to polyamine depletion suppresses tumor growth in...

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Detalles Bibliográficos
Autores principales: Hayes, Candace S, Burns, Mark R, Gilmour, Susan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976981/
https://www.ncbi.nlm.nih.gov/pubmed/24711956
http://dx.doi.org/10.4161/onci.27360