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Polyamine blockade promotes antitumor immunity
The levels of polyamines are elevated in neoplastic lesions as compared with normal tissues, and cancer cells tend to manifest a robust dependence on these compounds for proliferation and survival. We have recently demonstrated that a novel approach to polyamine depletion suppresses tumor growth in...
Autores principales: | Hayes, Candace S, Burns, Mark R, Gilmour, Susan K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976981/ https://www.ncbi.nlm.nih.gov/pubmed/24711956 http://dx.doi.org/10.4161/onci.27360 |
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