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Out of the bitter came forth sweet: Activating CD28-dependent co-stimulation via PD-1 ligands
Programmed cell death 1 (PDCD1, best known as PD-1) is a central negative regulator of effector T cells that is involved in the etiology of chronic inflammatory conditions, viral diseases, and cancer. We have recently sought to improve T-cell functions by means of a novel chimeric co-stimulatory mol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976982/ https://www.ncbi.nlm.nih.gov/pubmed/24711957 http://dx.doi.org/10.4161/onci.27399 |