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Membrane-bound KIT ligand-targeting DNA vaccination inhibits mammary tumor growth

We have recently demonstrated that a DNA vaccine targeting membrane-bound KIT ligand (KITL) inhibits tumor growth by interfering with vessel stabilization/permeability and by disrupting the recruitment of inflammatory cells and regulatory T cells, the latter being an essential mechanism by which tum...

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Detalles Bibliográficos
Autores principales: Dentelli, Patrizia, Cavallo, Federica, Brizzi, Maria Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976984/
https://www.ncbi.nlm.nih.gov/pubmed/24711955
http://dx.doi.org/10.4161/onci.27259