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The Cytotoxic Role of Intermittent High Glucose on Apoptosis and Cell Viability in Pancreatic Beta Cells

Objectives. Glucose fluctuations are both strong predictor of diabetic complications and crucial factor for beta cell damages. Here we investigated the effect of intermittent high glucose (IHG) on both cell apoptosis and proliferation activity in INS-1 cells and the potential mechanisms. Methods. Ce...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Li, Jing, Yang, Lei, Chen, Rongping, Yang, Rui, Zhang, Hua, Cai, Dehong, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977095/
https://www.ncbi.nlm.nih.gov/pubmed/24772447
http://dx.doi.org/10.1155/2014/712781