TET2 Promoter DNA Methylation and Expression Analysis in Pediatric B-cell Acute Lymphoblastic Leukemia

TET2 is a novel tumor suppressor gene involved in several hematological malignancies of myeloid and lymphoid origin. Besides loss-of-function mutations and deletions, hypermethylation of the CpG island at the TET2 promoter was found in human cancer. Previous analysis revealed no TET2 mutations in ac...

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Detalles Bibliográficos
Autores principales: Musialik, Ewa, Bujko, Mateusz, Wypych, Agnieszka, Matysiak, Michał, Siedlecki, Janusz Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977158/
https://www.ncbi.nlm.nih.gov/pubmed/24711921
http://dx.doi.org/10.4081/hr.2014.5333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977158/
https://www.ncbi.nlm.nih.gov/pubmed/24711921
http://dx.doi.org/10.4081/hr.2014.5333

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