In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes

Direct lineage conversion of adult cells is a promising approach for regenerative medicine. A major challenge of lineage conversion is to generate specific cell subtypes. The pancreatic islets contain three major hormone-secreting endocrine subtypes: insulin(+) β-cells, glucagon(+) α-cells, and soma...

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Detalles Bibliográficos
Autores principales: Li, Weida, Nakanishi, Mio, Zumsteg, Adrian, Shear, Matthew, Wright, Christopher, Melton, Douglas A, Zhou, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977343/
https://www.ncbi.nlm.nih.gov/pubmed/24714494
http://dx.doi.org/10.7554/eLife.01846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977343/
https://www.ncbi.nlm.nih.gov/pubmed/24714494
http://dx.doi.org/10.7554/eLife.01846

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