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Evaluation of GABAergic Transmission Modulation as a Novel Functional Target for Management of Multiple Sclerosis: Exploring Inhibitory Effect of GABA on Glutamate-Mediated Excitotoxicity

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS) where the communication ability of nerve cells in the brain and spinal cord with each other gets impaired. Some current findings suggest the role of glutamate excitotoxicity in the development and progr...

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Detalles Bibliográficos
Autores principales: Gilani, Ankit A., Dash, Ranjeet Prasad, Jivrajani, Mehul N., Thakur, Sandeep Kumar, Nivsarkar, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977453/
https://www.ncbi.nlm.nih.gov/pubmed/24778644
http://dx.doi.org/10.1155/2014/632376