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ALK-driven tumors and targeted therapy: focus on crizotinib

Receptor tyrosine kinases have emerged as promising therapeutic targets for a diverse set of tumors. Overactivation of the tyrosine kinase anaplastic lymphoma kinase (ALK) has been reported in several types of malignancies such as anaplastic large cell lymphoma, inflammatory myofibroblastic tumor, n...

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Detalles Bibliográficos
Autores principales: Murga-Zamalloa, Carlos, Lim, Megan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977456/
https://www.ncbi.nlm.nih.gov/pubmed/24715763
http://dx.doi.org/10.2147/PGPM.S37504