Design and Synthesis of New Dual Binding Site Cholinesterase Inhibitors: in vitro Inhibition Studies with in silico Docking

Cholinesterases (ChEs) play a vital role in the regulation of cholinergic transmission. The inhibition of ChEs is considered to be involved in increasing acetylcholine level in the brain and thus has been implicated in the treatment of Alzheimer’s disease. We have designed and synthesized a series o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yar, Muhammad, Bajda, Marek, Mehmood, Rana Atif, Sidra, Lala Rukh, Ullah, Nisar, Shahzadi, Lubna, Ashraf, Muhammad, Ismail, Tayaba, Shahzad, Sohail Anjum, Khan, Zulfiqar Ali, Naqvi, Syed Ali Raza, Mahmood, Nasir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977535/
https://www.ncbi.nlm.nih.gov/pubmed/24719609
http://dx.doi.org/10.2174/15701808113106660078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977535/
https://www.ncbi.nlm.nih.gov/pubmed/24719609
http://dx.doi.org/10.2174/15701808113106660078

Ejemplares similares