Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPARγ Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease

Comprehensive understanding of the precise mode of action/adverse outcome pathway (MoA/AOP) of chemicals becomes a key step towards superseding the current repeated dose toxicity testing methodology with new generation predictive toxicology tools. The description and characterization of the toxicolo...

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Detalles Bibliográficos
Autores principales: Al Sharif, Merilin, Alov, Petko, Vitcheva, Vessela, Pajeva, Ilza, Tsakovska, Ivanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977565/
https://www.ncbi.nlm.nih.gov/pubmed/24772164
http://dx.doi.org/10.1155/2014/432647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977565/
https://www.ncbi.nlm.nih.gov/pubmed/24772164
http://dx.doi.org/10.1155/2014/432647

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