Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir

[Image: see text] DNA transposases catalyze the movement of transposons around genomes by a cut-and-paste mechanism related to retroviral integration. Transposases and retroviral integrases share a common RNaseH-like domain with a catalytic DDE/D triad that coordinates the divalent cations required...

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Detalles Bibliográficos
Autores principales: Wolkowicz, Urszula M., Morris, Elizabeth R., Robson, Michael, Trubitsyna, Maryia, Richardson, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977574/
https://www.ncbi.nlm.nih.gov/pubmed/24397848
http://dx.doi.org/10.1021/cb400791u

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977574/
https://www.ncbi.nlm.nih.gov/pubmed/24397848
http://dx.doi.org/10.1021/cb400791u

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