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Interleukin-17 impedes Schwann cell-mediated myelination

BACKGROUND: Pro-inflammatory cytokines are known to have deleterious effects on Schwann cells (SCs). Interleukin 17 (IL-17) is a potent pro-inflammatory cytokine that exhibits relevant effects during inflammation in the peripheral nervous system (PNS), and IL-17-secreting cells have been reported wi...

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Detalles Bibliográficos
Autores principales: Stettner, Mark, Lohmann, Birthe, Wolffram, Kathleen, Weinberger, Jan-Philipp, Dehmel, Thomas, Hartung, Hans-Peter, Mausberg, Anne K, Kieseier, Bernd C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977670/
https://www.ncbi.nlm.nih.gov/pubmed/24678820
http://dx.doi.org/10.1186/1742-2094-11-63