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Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation

BACKGROUND: Signalling by the T cell antigen receptor (TCR) results in the activation of T lymphocytes. Nck1 and Nck2 are two highly related adaptor proteins downstream of the TCR that each contains three SH3 and one SH2 domains. Their individual functions and the roles of their SH3 domains in human...

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Autores principales: Ngoenkam, Jatuporn, Paensuwan, Pussadee, Preechanukul, Kanlaya, Khamsri, Boonruang, Yiemwattana, Ichaya, Beck-García, Esmeralda, Minguet, Susana, Schamel, Wolfgang WA, Pongcharoen, Sutatip
格式: Online 文件 Texto
语言:English
出版: BioMed Central 2014
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在线阅读:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977700/
https://www.ncbi.nlm.nih.gov/pubmed/24670066
http://dx.doi.org/10.1186/1478-811X-12-21