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Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells
BACKGROUND: AZD3514 inhibits and down regulates the androgen receptor (AR) and has undergone clinical trials in prostate cancer. To provide proof-of-mechanism (POM) in patients, an immunohistochemistry (IHC) method for determination of AR in circulating tumour cells (CTC) was developed and validated...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977890/ https://www.ncbi.nlm.nih.gov/pubmed/24674711 http://dx.doi.org/10.1186/1471-2407-14-226 |