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Computational Promoter Modeling Identifies the Modes of Transcriptional Regulation in Hematopoietic Stem Cells

Extrinsic and intrinsic regulators are responsible for the tight control of hematopoietic stem cells (HSCs), which differentiate into all blood cell lineages. To understand the fundamental basis of HSC biology, we focused on differentially expressed genes (DEGs) in long-term and short-term HSCs, whi...

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Detalles Bibliográficos
Autores principales: Park, Sung-Joon, Umemoto, Terumasa, Saito-Adachi, Mihoko, Shiratsuchi, Yoshiko, Yamato, Masayuki, Nakai, Kenta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977923/
https://www.ncbi.nlm.nih.gov/pubmed/24710559
http://dx.doi.org/10.1371/journal.pone.0093853