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Expression and characterization of a soluble VEGF receptor 2 protein

OBJECTIVE: To clone and express a truncated, soluble vascular endothelial growth factor receptor 2 (sVEGFR2) possessing the combined-functional domains 1–3 and 5 in eukaryotic cells and to test the inhibitory effects of full length VEGFR2 in vivo. RESULTS: pCMV6-trunctated-rVegfr2 (6100 bp) was succ...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhang, Xinyuan, Song, Ching, Bao, Shisan, Lai, Donna, Mou, Jianqiu, Jiang, Tao, Wang, Ningli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977943/
https://www.ncbi.nlm.nih.gov/pubmed/24618407
http://dx.doi.org/10.1186/2045-3701-4-14