Delay in cART Initiation Results in Persistent Immune Dysregulation and Poor Recovery of T-Cell Phenotype Despite a Decade of Successful HIV Suppression

BACKGROUND: Successful combination antiretroviral therapy (cART) increases levels of CD4+ T-cells, however this increase may not accurately reflect long-term immune recovery since T-cell dysregulation and loss of T-cell homeostasis often persist. We therefore assessed the impact of a decade of effec...

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Detalles Bibliográficos
Autores principales: Ndumbi, Patricia, Falutz, Julian, Pant Pai, Nitika, Tsoukas, Christos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977984/
https://www.ncbi.nlm.nih.gov/pubmed/24710051
http://dx.doi.org/10.1371/journal.pone.0094018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977984/
https://www.ncbi.nlm.nih.gov/pubmed/24710051
http://dx.doi.org/10.1371/journal.pone.0094018

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