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Modulation of the Human T Cell Response by a Novel Non-Mitogenic Anti-CD3 Antibody
The agonistic anti-human CD3ε antibody (Ab), OKT3, has been used to control acute transplant rejection. The in vivo administration of OKT3 was previously shown to induce the partial depletion of T cells and unresponsiveness (anergy) in the remaining CD4(+) T cells. However, this therapy is also asso...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978038/ https://www.ncbi.nlm.nih.gov/pubmed/24710513 http://dx.doi.org/10.1371/journal.pone.0094324 |