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Top-Down Proteomics with Mass Spectrometry Imaging: A Pilot Study towards Discovery of Biomarkers for Neurodevelopmental Disorders

In the developing mammalian brain, inhibition of NMDA receptor can induce widespread neuroapoptosis, inhibit neurogenesis and cause impairment of learning and memory. Although some mechanistic insights into adverse neurological actions of these NMDA receptor antagonists exist, our understanding of t...

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Detalles Bibliográficos
Autores principales: Ye, Hui, Mandal, Rakesh, Catherman, Adam, Thomas, Paul M., Kelleher, Neil L., Ikonomidou, Chrysanthy, Li, Lingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978070/
https://www.ncbi.nlm.nih.gov/pubmed/24710523
http://dx.doi.org/10.1371/journal.pone.0092831