Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential

Early T cell precursor acute lymphoblastic leukemia (ETP-ALL) exhibits lymphoid, myeloid, and stem cell features and is associated with a poor prognosis. Whole genome sequencing of human ETP-ALL cases has identified recurrent mutations in signaling, histone modification, and hematopoietic developmen...

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Detalles Bibliográficos
Autores principales: Treanor, Louise M., Zhou, Sheng, Janke, Laura, Churchman, Michelle L., Ma, Zhijun, Lu, Taihe, Chen, Shann-Ching, Mullighan, Charles G., Sorrentino, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978278/
https://www.ncbi.nlm.nih.gov/pubmed/24687960
http://dx.doi.org/10.1084/jem.20122727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978278/
https://www.ncbi.nlm.nih.gov/pubmed/24687960
http://dx.doi.org/10.1084/jem.20122727

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