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Why looking at the whole hippocampus is not enough—a critical role for anteroposterior axis, subfield and activation analyses to enhance predictive value of hippocampal changes for Alzheimer’s disease diagnosis

The hippocampus is one of the earliest affected brain regions in Alzheimer’s disease (AD) and its dysfunction is believed to underlie the core feature of the disease-memory impairment. Given that hippocampal volume is one of the best AD biomarkers, our review focuses on distinct subfields within the...

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Detalles Bibliográficos
Autores principales: Maruszak, Aleksandra, Thuret, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978283/
https://www.ncbi.nlm.nih.gov/pubmed/24744700
http://dx.doi.org/10.3389/fncel.2014.00095