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Molecular Interactions between Complement Factor H and Its Heparin and Heparan Sulfate Ligands
Complement factor H (CFH) is the major regulator of the central complement protein C3b in the alternative pathway of complement activation. A molecular view of the CFH interaction with native heparan sulfate (HS) is central for understanding the mechanism of how surface-bound CFH interacts with C3b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978290/ https://www.ncbi.nlm.nih.gov/pubmed/24744754 http://dx.doi.org/10.3389/fimmu.2014.00126 |