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Molecular Interactions between Complement Factor H and Its Heparin and Heparan Sulfate Ligands

Complement factor H (CFH) is the major regulator of the central complement protein C3b in the alternative pathway of complement activation. A molecular view of the CFH interaction with native heparan sulfate (HS) is central for understanding the mechanism of how surface-bound CFH interacts with C3b...

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Detalles Bibliográficos
Autores principales:	Perkins, Stephen J., Fung, Ka Wai, Khan, Sanaullah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978290/ https://www.ncbi.nlm.nih.gov/pubmed/24744754 http://dx.doi.org/10.3389/fimmu.2014.00126

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