Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice

Bax and Bak are critical effectors of apoptosis. Although both are widely expressed and usually functionally redundant, recent studies suggest that Bak has particular importance in certain cell types. Genetic and biochemical studies indicate that Bak activation is prevented primarily by Mcl-1 and Bc...

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Detalles Bibliográficos
Autores principales: Vandenberg, C J, Josefsson, E C, Campbell, K J, James, C, Lawlor, K E, Kile, B T, Cory, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978304/
https://www.ncbi.nlm.nih.gov/pubmed/24464220
http://dx.doi.org/10.1038/cdd.2013.201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978304/
https://www.ncbi.nlm.nih.gov/pubmed/24464220
http://dx.doi.org/10.1038/cdd.2013.201

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