Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas

Background: Epidermal growth factor receptor is overexpressed in most pediatric high-grade gliomas (HGG). Since erlotinib had shown activity in adults with HGG, we conducted a phase II trial of erlotinib and local radiotherapy (RT) in children with newly diagnosed HGG. Methods: Following maximum sur...

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Detalles Bibliográficos
Autores principales: Qaddoumi, Ibrahim, Kocak, Mehmet, Pai Panandiker, Atmaram S., Armstrong, Gregory T., Wetmore, Cynthia, Crawford, John R., Lin, Tong, Boyett, James M., Kun, Larry E., Boop, Fredrick A., Merchant, Thomas E., Ellison, David W., Gajjar, Amar, Broniscer, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978340/
https://www.ncbi.nlm.nih.gov/pubmed/24744992
http://dx.doi.org/10.3389/fonc.2014.00067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978340/
https://www.ncbi.nlm.nih.gov/pubmed/24744992
http://dx.doi.org/10.3389/fonc.2014.00067

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